N-ALPHA-ACETYL-L-GLUTAMIC ACID
Acetyl glutamic acid
CAS: 1188-37-0
Molecular Formula: C7H11NO5
N-ALPHA-ACETYL-L-GLUTAMIC ACID - Names and Identifiers
| Name | Acetyl glutamic acid |
| Synonyms | Ac-Gly N-AC-L-GLU l-glutamicaci N-ACETYL-L-GLU N-Acetylglutamate acetylglutamicacid Acetyl glutamic acid N-Acetyl-L-glutamate N-acetylglutamic acid ACETYL-L-GLUTAMIC ACID Acetyl-L-glutamic acid N-ACETYL-L-GLUTAMIC ACID N-Acetyl-L-glutamic acid L-Glutamic acid, N-acetyl- N-ALPHA-ACETYL-L-GLUTAMIC ACID (2S)-2-(acetylamino)pentanedioate |
| CAS | 1188-37-0 |
| EINECS | 214-708-4 |
| InChI | InChI=1/C7H11NO5/c1-4(9)8-5(7(12)13)2-3-6(10)11/h5H,2-3H2,1H3,(H,8,9)(H,10,11)(H,12,13)/p-2/t5-/m0/s1 |
N-ALPHA-ACETYL-L-GLUTAMIC ACID - Physico-chemical Properties
| Molecular Formula | C7H11NO5 |
| Molar Mass | 189.17 |
| Density | 1.4119 (rough estimate) |
| Melting Point | 194-196°C(lit.) |
| Boling Point | 324.41°C (rough estimate) |
| Specific Rotation(α) | -16 º (c=1, water) |
| Flash Point | 253.7°C |
| Water Solubility | 2.7 g/100 mL (20 ºC) |
| Solubility | Easily soluble in water, soluble in ethanol and ethyl acetate. |
| Vapor Presure | 3.48E-11mmHg at 25°C |
| Appearance | White crystal |
| Color | White |
| BRN | 1727473 |
| pKa | 3.45±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | -15 ° (C=1, H2O) |
| MDL | MFCD00002802 |
| Use | Mainly used as pharmaceutical intermediates, biochemical reagents, resolution reagents |
N-ALPHA-ACETYL-L-GLUTAMIC ACID - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 2 |
| RTECS | LZ9725000 |
| TSCA | Yes |
| HS Code | 29241900 |
N-ALPHA-ACETYL-L-GLUTAMIC ACID - Reference
| Reference Show more | 1. Guizi Peng, Xin Pan, Haiyan Hu, Yuehong Xu, Chuanbin Wu, N-terminal site-specific PEGylation enhances the circulation half-life of Thymosin alpha 1, Journal of Drug Delivery Science and Technology, Volume 49, 2019, Pages 405-412, ISSN 1773-2247, https://do 2. [IF=3.981] Guizi Peng et al."N-terminal site-specific PEGylation enhances the circulation half-life of Thymosin alpha 1."J Drug Deliv Sci Tec. 2019 Feb;49:405 3. [IF=2.752] Yuting Zhang et al."Metabolomic Analysis and Identification of Sperm Freezability-Related Metabolites in Boar Seminal Plasma."Animals-Basel. 2021 Jul;11(7):1939 |
N-ALPHA-ACETYL-L-GLUTAMIC ACID - Reference Information
| FEMA | 4752 | N-ACETYL GLUTAMATE |
| NIST chemical information | Information provided by: webbook.nist.gov (external link) |
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| Biological activity | N-Acetylglutamic acid (N-Acetylglutamate) is the first intermediate involved in arginine biosynthesis in prokaryotes and simple eukaryotes, and is a regulator of the urea cycle. |
| uses | mainly used as pharmaceutical intermediates, biochemical reagents, splitting reagents, etc. used in biochemical research, used in medicine as brain function improvement drugs, used for liver coma, brain trauma, brain tumors, paralysis, mental retardation, memory disorders and other diseases. |
Last Update：2024-04-09 15:16:47
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